Diagnostic - available allergens

For in vivo diagnostic of type I allergies

HAL Allergy offers a wide range of diagnostics portfolio including different apllication forms:

  • Skin Prick Test
  • Provocation Spray
  • Provocation Dilution

The portfolio includes relevant allergens in order to allow for a proper allergy test.

Allergen (Category) HAL Allergy Prick Test HAL Allergy Provo Spray HAL Allergy Provo Test
    07-08 Secale cereale (Rye) ■ (1)    
    07-11 Phleum pratense    
■ (1)    
    07-30 Mixed Grasses
    (9 grasses + Secale)
■ (1)  
    40-01 Triticum sativum
■ (1)    
    11-01 Corylus avellana
■ (1)    
    11-02 Betula verrucosa
■ (1) ■ (1) ■ (1)
    11-04 Alnus glutinosa
■ (1)    
    11-30 Spring trees
    (Betula, Alnus, Corylus)
■ (1)    
    11-05 Quercus robur
■ (1)    
    11-06 Fraxinus excelsior
■ (1) ■ (1)  
    11-07 Fagus sylvatica   
■ (1)    
    08-01 Urtica dioica
■ (1)    
    08-02 Plantago lanceolata
■ (1) ■ (1)  
    09-01 Artemisia vulgaris
■ (1) ■ (1)  
    11-11 Platanus acerifolia
    (Plane tree)
    14-07 Ambrosia elatior  
■ (1) ■ (1)  
    18-01 Aspergillus fumigatus ■ (1) ■ (1) ■ (1)
    20-01 Alternaria alternata ■ (1) ■ (1) ■ (1)
    15-01 Dog ■ (1) ■ (1)  
    15-02 Cat ■ (1) ■ (1)  
    02-00 Derm. pteronyssinus ■ (1) ■ (1) ■ (1)
    02-01 Derm. farinae ■ (1) ■ (1) ■ (1)
    34-01 Peanut ■ (1)    
    34-03 Hazelnut ■ (1)    
    Negative control ■ (1) ■ (1) ■ (1)
    Histamine  ■ (1) ■ (1) ■ (1)

Histamine dilution series for nonspecific bronchial provocation available in the concentrations: 1.0 mg/ml, 2.0 mg/ml, 4.0 mg/ml, 8.0 mg/ml, 16.0 mg/ml. (1)

Availibility: (1) Germany 

Status per 22.08.2016

Summary leaflet: Skin-prick test, Intracutaneous test, Nasal and bronchial provocation test

Composition: Allergens extracts from pollen, mites, epithelia, moulds, flours or food; solution. Indications: Diagnosis of IgE-mediated sensitization to the respective allergen or to establish the atopic status of the patient. Dosage and administration: Skin tests are performed on the volar site of the fore arm or on the back. It is possible to test fore several allergens at the same time. After approximately 20 minutes the result is read. Skin-prick test: A drop of each of the allergens is applied separately in appropriate distance (approx. 4 cm) on dry skin. The puncture is carried out with a sterile lancet through the drop of the allergen. Intracutaneous test: 0.02 – 0.05 ml of allergen solution is administered intracutaneously using a disposable tuberculin syringe. Nasal test: The nose should be cleaned thoroughly before the test is performed. The allergen solution is sprayed or dripped with a syringe into the nose. The assessment can be done with a rhinomanometer and/or assessment of symptoms (e.g. sneezing) before and after the administration of the allergen solution. Bronchial test: several increasing concentrations of an allergen solution are sprayed into the bronchia/lungs and inhaled. After 20 minutes a higher concentration is administered if no or little reaction is observed after the first administration. The symptoms (e.g. coughing) and/or lung function will be assessed. The patient will be under surveillance of medical personnel until 2 hours after the administration and in case of the other tests 30 minutes. For all the tests a negative check (allergen free solvent) and a positive check (with a solution of histamine) should always be carried out. Contraindications: Hypersensitivity to any of the excipients. Skin tests: the skin on the test site is damaged, secondary skin infection. Provocation test: diseases which influence the general condition of the patient, acute severe allergic symptoms. Nasal test: cold or acute nasal cavity infections, nasal operations less than 8 weeks ago. Bronchial test: serious and uncontrolled asthma, limited lung function, symptoms that make the assessment impossible. Relative: Pregnancy, treatment with β-blockers, children under the age of 3 (skin or nasal tests) or 5 years (bronchial test), cardiovascular diseases with increased risks using adrenalin, extreme sensitivity. Skin tests: secondary inflammatory or secondary degenerative skin diseases and generalized urticaria, diseases, acute and chronic eczema or lesion in the test area. Bronchial test: airway infections in the last 2 weeks, spasm of the airways that needed treatment. Special warnings and special precautions for use: The reaction of the tests can be influenced by high exposure to allergens (e.g. during the pollen season). Side effects: In highly sensitized patients intensified allergic reactions may occur. These reactions may show up as intensified reaction at the test  site, reappearance of patient specific allergic symptoms as a mild systemic reaction (itching of eyes, running or stuffed nose, sneezing, coughing, atopic eczema), intensified systemic reactions (shortness of breatch, generalized urticaria, Quinke oedema),in extremely cases also anaphylactic shock. These reactions generally occur within 20 minutes or even several hours after allergen application. Package: The skin-prick test is packed in a 3 ml multidose glass vial with a pipette. The intracutaneous and bronchial provocation test are both packed in a 5 ml multidose glass vial with stopper and aluminium cap. The nasal provocation test is packed in a 5 ml multidose glass vial with sprayer.

The complete product information is available on request. HAL Allergy BV, P.O. Box 1007, 2001 BA  Haarlem, The Netherlands.  Date: May 2007